What is one known cause of postrenal failure?

Postrenal failure refers to a type of acute kidney injury that occurs as a result of obstruction of urine flow after it has been formed. One known cause of postrenal failure is prostate disease, particularly conditions such as benign prostatic hyperplasia (BPH) or prostate cancer. These conditions can lead to obstruction of the urinary tract, preventing urine from exiting the bladder and causing a backup of urine, which ultimately affects kidney function.

The obstruction can lead to increased pressure in the urinary system, impacting the ability of the kidneys to filter blood effectively. This pressure can result in damage to the renal tissues and ultimately lead to renal failure. Understanding the role of prostate disease in obstructing urine flow helps clarify the mechanism by which it contributes to postrenal failure.

Other conditions that could potentially lead to postrenal failure, such as renal trauma, fluid volume shifts, and kidney infections, are associated with different mechanisms that primarily affect kidney structure or function in various ways. However, in the context of urinary obstruction specifically leading to postrenal failure, prostate disease stands out as a significant cause.